As part of the MVP Infographic Series this post explores “Thrombolysis with alteplase 3 to 4.5 hours after acute ischemic stroke” published by Hacke et al 2008.1 Alteplase is a tissue plasminogen activator used for intravenous thrombolysis treatment of acute ischemic strokes. Prior to this study, Alteplase was only approved until 3hrs following stroke symptom onset. The authors sought to assess the efficacy and the rates of adverse events including haemorrhage of Alteplase … Continue reading CanadiEM MVP Infographic Series – Thrombolysis with Alteplase 3 to 4.5 Hours After Acute Ischemic Stroke