CanMEDS Roles addressed: Expert Main Messages At standard doses DOACs are safe and effective for most patients and lab monitoring is not required for routine use. If the time of the last dose is known, an estimate of current anticoagulation effect can be obtained by measuring the number of half-lives that have elapsed in those with normal renal function. If the last ingestion is unknown, an estimate of current anticoagulation effect can be …
Blood & Clots Series: What are the risks of reversing anticoagulation?
All the content from the Blood & Clots series can be found here. CanMEDS Roles addressed: Medical expert, Communicator Case Description You are working a shift in your local emergency department and an 89-year-old female is brought in with a 2-day history of melena stool. The patient has a history of atrial fibrillation and uncontrolled hypertension despite being on an ACE-inhibitor. Her initial bloodwork shows a hemoglobin of 102 g/L (no baseline provided), …
Blood & Clots Series: When and how should I reverse anticoagulation with warfarin?
All the content from the Blood & Clots series can be found here. CanMEDS Roles addressed: Medical Expert Case Description You are in the emergency department seeing an 89-year-old female presenting with five episodes of coffee ground emesis over the last twenty-four hours. She has atrial fibrillation and is on long-term warfarin for stroke prevention. She also has CAD and had two drug eluting stents placed 4 years ago but is no longer …
Blood and Clots Series: What are the complications of transfusion? What symptoms/signs should I worry about?
All the content from the Blood & Clots series can be found here. CanMEDS Roles addressed: Medical Expert, Communicator, Leader Case Description You are a resident physician rotating through the ICU. You’ve been taking care of a 32-year-old woman who sustained injuries in a high-speed motor vehicle collision two days ago. She is now stable and extubated in the ICU. Her hemoglobin has been stable in the 80s since arriving in the ICU …
Blood and Clots Series: Massive transfusion protocol: what is it, why does it exist, and when should I call one?
All the content from the Blood & Clots series can be found here. CanMEDS Roles addressed: Medical Expert Case Description A 32-year old woman presents to the ED following a motor vehicle collision with lateral impact (T-bone collision) and is brought into the trauma bay. Significant bleeding was reported on scene and the patient arrives looking diaphoretic, pale, and unwell. Vitals in the trauma bay are BP 104/64 mmHg, HR 128, RR 22 …