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Methoxyflurane- an alternative to opioid and NSAID analgesia in the Emergency Department?

In Medical Concepts by Jeremi LaskiLeave a Comment

Introduction Methoxyflurane, also known as Penthrox, is an inhaled analgesic that was first used in the early 1960s for general anaesthesia.​1​ While initially popular, reports of serious side effects including hepatotoxicity and irreversible dose-dependent nephrotoxicity led to its reduced usage as a general anesthetic by the 1970s.​2​ Nevertheless, due to its non-opioid nature and short half-life, methoxyflurane has found new life as a short acting analgesic for moderate to severe pain in several …